BDBM50556434 CHEMBL4763661
SMILES O=C(Nc1nc(c(s1)C(=O)c1ccc(cc1)-c1ccccc1)-c1ccccc1)C1(CC1)c1ccc2OCOc2c1
InChI Key InChIKey=SQGNZRHAKXSLOB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50556434
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataKd: 8.93E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa
Curated by ChEMBL
University Of Genoa
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair